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Tutor profile: Madhu B.

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Madhu B.
PhD Scholar, 5-6 yrs of experience of mentoring post graduate traniees,
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Questions

Subject: Biomedical Science

TutorMe
Question:

Taking paracetamol in the absence of fever will lead to a drop in body temperature. True or false?

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Madhu B.
Answer:

False. Paracetamol is a centrally acting analgesic and antipyretic drug which acts by inhibiting prostaglandin. It reduces fever by promoting heat loss (through sweating and cutaneous vasodilation) and thus helps reset the hypothalamic thermostat. Thus, under normal conditions when body temperature is maintained, paracetamol will have no effects on body temperature.

Subject: Biochemistry

TutorMe
Question:

How can one differentiate between a solution of protein and DNA without using a spectrophotometer?

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Madhu B.
Answer:

By shaking both the solutions one can differentiate between the two solutions, the one that will have frothing will be the one that has proteins in it. Protein molecules upon shaking losses their tertiary and secondary structure and their hydrophobic sides interact with each other while hydrophilic sides interact with the air around and thus leading to trapping of air bubbles. Leading to formation of foam. This does not happen with DNA though.

Subject: Biology

TutorMe
Question:

What is the importance of telomeres in cellular aging?

Inactive
Madhu B.
Answer:

A telomere is repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. In humans, this sequence is repeated approximately 2,500 times. During chromosome replication, the enzymes that duplicate DNA cannot continue their duplication all the way to the end of a chromosome, so the end of the chromosome is shortened in each duplication. This protects important genes from getting truncated. Eventually, telomeres get too short to do their job, causing our cells to age and stop functioning properly. Therefore, telomeres act as the aging clock in every cell.

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