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Tutor profile: Patrick M.

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Patrick M.
Recent Medical School Graduate
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Questions

Subject: Medicine

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Question:

A 15-month old boy is brought to the office due to 3 days of fever. In the past 9 months, he has had 4 episodes of otitis media and 2 episodes of lobar pneumonia, one of which required hospitalization and prolonged intravenous antibiotic therapy. The patient is at the 40th percentile for weight. His temperature is 38.2 C (100.8 F). Physical examination shows a bulging, erythematous tympanic membrane on the right side but is otherwise unremarkable. The patient’s laboratory studies are as follows: Leukocytes – 8,000/mm^3 Neutrophils - 6,000/mm^3 Lymphocytes - 2,000/mm^3 CD4 T cells - 1,150/mm ^3 (640-1175/mm^3) CD8 T cells - 810/mm^3 (335-875/mm^3) Immunoglobulins IgG - 80 mg/dL (700-1500 mg/dL) IgA - 31 mg/dL (60-400 mg/dL) IgM - 11 mg/dL (60-300 mg/dL) Which of the following is the most likely diagnosis for this patient? A. Bruton agammaglobulinemia B. Common variable immunodeficiency C. DiGeorge syndrome D. Severe combined immunodeficiency E. Transient hypogammaglobulinemia of infancy

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Patrick M.
Answer:

A. Bruton agammaglobulinemia - There are low levels of Ig as well as low levels of B cells, but normal levels of T cells, ruling out SCID. CVID would have a milder clinical course and would show a later onset of age for the test. DiGeorge Syndrome would have low T cell due to thymic hypoplasia (remember CATCH-22 mnemonic).

Subject: Biology

TutorMe
Question:

Which of the following is true regarding the nucleus? I. It contains a phospholipid bilayer II. The nucleolus is the site of ribosome synthesis III. It contains nuclear pores through which mRNA and DNA can exit to the cytosol

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Patrick M.
Answer:

I and II The cell’s nucleus, often termed the control center of the cell, is a very important organelle that contains the DNA. The nucleus is surrounded by two cell membranes, made up of two phospholipid bilayers, called the nuclear envelope; therefore, statement I is true. The nucleus also contains a nucleolus, which is the site of rRNA synthesis. rRNA, or ribosomal RNA, are the building blocks for ribosomes and are assembled into ribosomal subunits in the nucleolus. Statement II is true. The nucleus does contain nuclear pores, however, DNA cannot exit the nucleus. Messenger RNA (mRNA), on the other hand, can exit the nucleus and enter the cytosol, where it can bind to ribosomes and undergo translation; therefore, statement III is false.

Subject: Algebra

TutorMe
Question:

Solve the equation $$x^2 – 10 x = –16$$ by using the completing the square method.

Inactive
Patrick M.
Answer:

Multiply coefficient of “ x‐term” by equation Square the result. $$(–5)^ 2 = 25$$ Add 25 to both sides of the equation. $$x^2-10x+25=-16+25$$ $$(x-5)^2=9$$ $$x-5= +/- \sqrt{9}$$ $$x=3+5 = 8$$ or $$x= -3+5 = 2$$

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