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# Tutor profile: Joe W.

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Joe W.
Medical Student
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## Questions

### Subject:SAT

TutorMe
Question:

If Jack is 10 years old and his sister is 4 years less than double his age, what will Jack's age be when his sister is 50?

Inactive
Joe W.

These questions can be confusing, so it's best to break it down one step at a time. First step: Jack's sister's age - Jack is 10, and his sister is 4 years less than double his age - 10x2= 20 (Double his age) - 20-4= 16 (4 years less than double) So Jack's sister is 16 years old Second step: How old is Jack when his sister is 50 years old? - If Jack is 10 when his sister is 16, then his sister is 6 years older than him - That means that when she is 50, she will still be 6 years older than him - 50-6=44 So Jack will be 44 years old when his sister is 50 years old

### Subject:Basic Chemistry

TutorMe
Question:

Why can competitive inhibitors be outweighed by adding more substrate, but noncompetitive inhibitors are not affected by increased substrate?

Inactive
Joe W.

The difference lies in the mechanism of the two different inhibitors. Competitive inhibitors "compete" with the substrate by binding to the same spot on an enzyme. There are only a limited amount of binding sites, and these will be occupied by either the substrate or the inhibitor. Therefore, the more sites occupied by inhibitor, the less sites available for the substrate to bind. If you increase the amount of substrate molecules available, sites are more likely to be filled by substrate, because there is more substrate competing for those spots. Noncompetitive inhibitors, on the other hand, bind to a different site on an enzyme than the substrate. They are not competing for the same site, so increasing substrate has no effect on the number of binding sites for the noncompetitive inhibitor.

### Subject:Biology

TutorMe
Question:

Alterations in DNA sequences can have a wide range of effects on an organism, ranging from death to no significant symptoms. Please explain why there is such a large range in possible outcomes.

Inactive
Joe W.

The effect of an alteration to DNA sequence depends on the exact type of alteration that occurs. The problems arise when that DNA undergoes transcription and translation to make a protein product. The DNA sequence itself acts almost as an "instruction manual" for protein synthesis. The exact DNA sequence encodes for specific amino acids that make up a protein. If the DNA alteration results in changes to the protein makeup, the protein may end up dysfunctional. If the protein is dysfunctional, the actions of this protein will not occur. Depending on the importance of the protein, the effects can be anywhere from insignificant to life threatening.

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