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Tutor profile: Brett C.

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Brett C.
Bachelor of Science in Biomedical Sciences, Medical Student, tutored throughout undergrad
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Questions

Subject: Health and Medicine

TutorMe
Question:

Courses like Anatomy and Physiology can be very challenging. How does excretion and reabsorption work in the kidney? What pressures make up the glomerular filtration pressure?

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Brett C.
Answer:

Just like in systemic capillaries, filtration is a balance between the pressures that push fluid out of the capillary vs those that hold fluid in. The two basic pressures are the Hydrostatic Pressure (blood pressure) in the capillary, pushing fluid out, and the Colloid Osmotic Pressure, pulling fluid back in. The Hydrostatic Pressure is the same as blood pressure, which is 55 mm Hg as blood enters the glomerulus. The Colloid Osmotic Pressure results from the high concentrations of proteins in the plasma, setting up a Gibbs-Donnan equilibrium across the capillary wall, pulling in ions and osmotically obligated water. That pressure is 30 mm Hg. But in Bowman’s Capsule, there is a third pressure that you have to deal with: Capsular Hydrostatic Pressure – the pressure of the fluid in the BC pushing back against the capillary. That is 15 mm Hg. So in this case, the net filtration pressure is 55 – 30 – 15 = 10 mm Hg pushing fluid and solutes across the capillary wall into the Bowman's capsule

Subject: Biochemistry

TutorMe
Question:

This course ranges in material from amino acids and protein folding to the overview of how we form energy and maintain a healthy metabolism. When you're busy cramming for your other classes, understanding the difference between glycolysis, gluconeogenesis, glycogenesis, and glyconeogenesis can be very intimidating. Do you need help?

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Brett C.
Answer:

Glycolysis - The breakdown of glucose to 2 pyruvate molecules to yield energy. It releases a moderate amount of energy captured in two substrate-level phosphorylation and one oxidation reaction. It has an energy investment and energy payoff stage. Gluconeogenesis - The combination of small carbon-containing compounds to yield glucose. It is the reverse process of glycolysis, except three enzymes have been replaced due to their highly exergonic nature in glycolysis. Glycogenesis - Glycogen is a branched polymer of glucose in a storage form; this is the process of synthesizing glycogen molecules. It occurs when blood glucose levels are high. Glycogenolysis - The process of breaking down glycogen. It occurs when glucose is needed.

Subject: Basic Chemistry

TutorMe
Question:

Equilibrium? Acids and bases? ICE Tables? General Chemistry can be a confusing class.

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Brett C.
Answer:

While these subjects may be daunting, I will help you work through this subject with simple explanations while I provide you with the tips and tricks that will help you succeed in this course.

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