Tutor profile: Jason C.
Subject: Quality Management
You are reviewing a report that details a recent deviation from standard operating procedures. Within the report a CAPA is outlined but you do not believe that the CAPA is adequate to address the root cause(s) of the deviation. What are your next steps?
Discuss the CAPA and root causes with the author of the report. CAPAs should be specific, measurable, and should be revisited frequently to assess effectiveness. CAPAs that are intended to be long term should be written into new procedures so as to prevent further deviations.
Subject: Health and Medicine
A 55 year old man visits his physician for a routine medical examination and is prescribed an ACE inhibitor to control his high blood pressure. The patient returns two weeks later complaining of a cough that is irritating his throat. This cough is directly related to an increase in what substance in this patient?
ACE inhibitors decrease the breakdown of bradykinin. The excess bradykinin can lead to a benign cough in the patient.
A 15 year old boy played soccer outside in the hot sun all day long. His mother brought him into the emergency room because he was lethargic and vomited twice. His oral mucus membranes are dry. How would you expect his renal system to compensate for the dehydration and what are the effects of that compensation?
Increase renin release by the kidneys which would lead to conversion of angiotensinogen to angiotensin I.
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